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High-Performance Computing Principal Engineer

Elanco
Indianapolis, IN Full-time 11/18/2025
Master's with 2+ Years of Experience

Job Description

Elanco is seeking a High-Performance Computing (HPC) Principal Engineer to lead the technical direction and strategy for Elanco's HPC ecosystem.

Requirements

  • Bachelor's or Master's degree in Computer Science, Engineering, or a related technical field
  • Deep expertise in Linux/Unix system administration in a large-scale environment
  • Broad experience with HPC cluster management, including job schedulers and parallel file systems
  • Exceptional scripting skills for automation, particularly in Python and Bash
  • Solid understanding of high-speed networking fabrics like InfiniBand or Omni-Path
  • Familiarity with Public Cloud services, specifically Microsoft Azure and Google Cloud Platform (GCP)
  • Proven experience with DevSecOps concepts and tooling
  • Excellent analytical and troubleshooting skills
  • Strong interpersonal and communication skills
  • Proven experience leading complex technical projects and mentoring engineers

Responsibilities

  • Shape the design and architecture of Elanco’s HPC infrastructure
  • Evaluate emerging technologies and build business cases for new investments
  • Act as a mentor and technical escalation point for other engineers
  • Design, deploy, configure, and maintain HPC clusters and associated infrastructure
  • Proactively monitor system performance and optimize efficiency
  • Provide user support and guidance on leveraging HPC resources
  • Develop and maintain automation tools for system administration tasks
  • Manage job scheduling systems for efficient resource allocation
  • Implement and maintain security best practices for sensitive data
  • Collaborate with stakeholders for capacity planning and strategic evolution of HPC capabilities

Benefits

  • Employees at Elanco are often offered competitive compensation with annual bonus and equity eligibility, retirement plans (including a U.S. 401(k)), and comprehensive health coverage—medical, dental, vision, company-paid life and disability—and even pet insurance. Time-off and flexibility typically include generous PTO, U.S. mid-year and year-end paid shutdown weeks, parental leave, and flexible/remote work options. Employees also benefit from strong development programs (onboarding, course libraries, mentorship, nine ERGs, and tiered leadership programs) that support both professional growth and community involvement.