Job Description

Elanco is seeking an In vitro Assay Development Scientist to lead method transfer and train junior scientists in the development and optimization of cell-based and biochemical assays. This role involves collaboration in a cross-functional environment to characterize small molecule compounds and contribute to the innovation pipeline.

Requirements

B.S. degree
Minimum 20 years relevant academic or industry experience in method transfer and training of junior scientists
Experience with various assay detection technologies (e.g., absorbance, fluorescence, luminescence) and data analysis software

Responsibilities

Lead method transfer and training of junior scientists in cell-based and biochemical assay development and optimization
Collaborate cross-functionally in the build-out of new Discovery Bioassay capabilities at the new Indianapolis HQ
Design, develop, and validate novel and robust cell-based and enzymatic assays suitable for high-throughput screening (HTS)
Characterize protein inhibitors by determining IC50 values, potency (Ki), and their mechanism of inhibition
Implement and execute screening funnels to evaluate compound libraries, generating high-quality, reproducible data to drive structure-activity relationship (SAR) analysis
Collaborate internally and externally with protein production to ensure the availability of high-quality, active protein preparations for use in assays
Proactively research and implement new assay technologies, detection methods, and instrumentation to increase assay quality and efficiency
Analyze, interpret, and present complex experimental data to colleagues within project teams
Troubleshoot assays to ensure high-quality, reproducible results
Stay current with scientific literature and proactively evaluate new technologies, instrumentation, and methodologies to improve assay performance and throughput
Maintain records of experimental designs, protocols, and results in electronic lab notebooks (ELN)

Benefits

Employees at Elanco are often offered competitive compensation with annual bonus and equity eligibility, retirement plans (including a U.S. 401(k)), and comprehensive health coverage—medical, dental, vision, company-paid life and disability—and even pet insurance. Time-off and flexibility typically include generous PTO, U.S. mid-year and year-end paid shutdown weeks, parental leave, and flexible/remote work options. Employees also benefit from strong development programs (onboarding, course libraries, mentorship, nine ERGs, and tiered leadership programs) that support both professional growth and community involvement.