JobsSenior Scientist, Upstream Process Development (Mammalian Cell Culture)
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Senior Scientist, Upstream Process Development (Mammalian Cell Culture)

Elanco

Location

Indianapolis, IN

Type

Full-time

Posted

5/14/2026

Compensation

Not listed

Undergraduate with 5+ Years of Experience
Approval 98.6%·Filings 69·New hires 31·
Established Sponsor
·FY 2025

Job description

The Upstream Senior Research Scientist at Elanco will be a key technical leader in the Technical Development organization, focusing on advancing the biologics portfolio, including monoclonal antibodies, recombinant proteins, and vaccines. This role involves leading the design, optimization, and scaling of mammalian cell culture processes. The scientist will collaborate with cross-functional teams to shape the future of the upstream platform and contribute to bringing next-generation therapies from the lab to manufacturing. The position emphasizes innovation and technical mentorship within a diverse and inclusive work environment.

Requirements

  • PhD in Chemical Engineering, Biochemistry, Biotechnology, or a related scientific field; OR a Master's degree with 3+ years of relevant experience; OR a Bachelor's degree with 5+ years of relevant experience.
  • Hands-on experience in upstream process development for mammalian cell culture, including direct experience with bioreactor operations at the bench or pilot scale.
  • Demonstrated ability to apply scientific principles to solve process development challenges, coupled with a foundational knowledge of experimental design, data analysis, and process scale-up principles.

Responsibilities

  • Lead upstream process development for mammalian cell culture systems, including bioreactor optimization, process characterization, and scale-up from bench to pilot scale.
  • Design and execute experiments utilizing Design of Experiments methodologies to enhance cell culture performance, product yield, and process robustness.
  • Drive the development of new upstream platforms, including the formulation and optimization of novel basal and feed media for CHO cell culture systems.
  • Lead the technology transfer of upstream processes to manufacturing sites, ensuring process scalability and authoring technical documents.
  • Collaborate with cross-functional teams and provide technical mentorship to junior scientists to advance biologics production.

Benefits

  • Employees at Elanco are often offered competitive compensation with annual bonus and equity eligibility, retirement plans (including a U.S. 401(k)), and comprehensive health coverage—medical, dental, vision, company-paid life and disability—and even pet insurance. Time-off and flexibility typically include generous PTO, U.S. mid-year and year-end paid shutdown weeks, parental leave, and flexible/remote work options. Employees also benefit from strong development programs (onboarding, course libraries, mentorship, nine ERGs, and tiered leadership programs) that support both professional growth and community involvement.

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