The Senior Research Scientist in the Mechanistic Biology team at Elanco will lead target identification and validation for animal diseases to enhance the drug discovery pipeline. This non-lab role focuses on guiding cross-functional teams through early-stage drug discovery using advanced techniques and AI/ML-driven platforms. The position emphasizes accelerating the discovery cycle through high-throughput screening approaches for both small molecules and biologics. The ideal candidate will contribute to innovative strategies that improve animal health and foster collaboration across various scientific disciplines.

• Ph.D. in Cell/Molecular Biology, Pharmacology, Biochemistry, or a related field with several years of postdoctoral training.
• Professional experience in industry research and early-stage biotech/drug discovery, including CRO management.
• Expertise in target identification and validation, including biological assay development for small/large molecules.
• Expertise in New Approach Methodologies (NAMs) such as organoids/iPSCs and CRISPR/Cas9 screening.

• Lead the identification and prioritization of novel targets using in vitro/in vivo experiments, literature reviews, bioinformatics, functional genomics, and AI/ML.
• Design and deploy high-throughput and multi-modal screening strategies to identify novel chemical and biological starting points.
• Guide cross-functional teams through early drug discovery from initial concept through target validation.
• Develop strategies to de-risk targets and enhance commercial viability by integrating Chemistry, Manufacturing, and Controls considerations.
• Manage external CRO partnerships and biotech collaborations, providing scientific expertise to support discovery campaigns.

• Employees at Elanco are often offered competitive compensation with annual bonus and equity eligibility, retirement plans (including a U.S. 401(k)), and comprehensive health coverage—medical, dental, vision, company-paid life and disability—and even pet insurance. Time-off and flexibility typically include generous PTO, U.S. mid-year and year-end paid shutdown weeks, parental leave, and flexible/remote work options. Employees also benefit from strong development programs (onboarding, course libraries, mentorship, nine ERGs, and tiered leadership programs) that support both professional growth and community involvement.